KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKB
All Species:
5.45
Human Site:
T69
Identified Species:
9.23
UniProt:
Q96GD4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96GD4
NP_004208.2
344
39280
T69
S
G
T
P
D
I
L
T
R
H
F
T
I
D
D
Chimpanzee
Pan troglodytes
XP_511856
395
44529
T120
S
G
T
P
N
I
L
T
R
H
F
T
I
D
D
Rhesus Macaque
Macaca mulatta
XP_001118154
562
62706
M287
S
G
T
P
N
I
L
M
R
H
F
T
I
D
D
Dog
Lupus familis
XP_849906
346
39574
M69
S
G
I
P
N
F
S
M
R
S
F
T
I
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O70126
345
39306
Q69
S
Q
G
S
T
A
S
Q
G
S
Q
N
K
Q
P
Rat
Rattus norvegicus
O55099
343
39216
S69
G
A
T
A
L
Q
G
S
Q
S
R
Q
P
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
E69
V
L
F
K
G
Q
L
E
K
A
G
V
E
H
Q
Chicken
Gallus gallus
XP_425725
409
46456
K139
K
K
K
E
E
T
K
K
R
Q
W
S
L
D
D
Frog
Xenopus laevis
Q6DE08
361
41717
K85
T
A
L
A
E
M
P
K
R
K
F
T
I
D
D
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
L69
G
K
F
G
N
V
Y
L
A
R
E
R
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
R73
R
V
Y
L
A
R
E
R
H
S
H
Y
L
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
H73
L
I
S
G
G
V
E
H
Q
L
E
R
E
I
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M077
294
33954
Q66
L
K
V
L
F
K
S
Q
L
Q
Q
S
Q
V
E
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
F96
E
N
K
K
L
P
K
F
K
S
L
S
L
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
60.3
91.3
N.A.
84.9
84.5
N.A.
61.9
56.9
67.5
66.5
N.A.
44.4
N.A.
53.4
N.A.
Protein Similarity:
100
86.3
60.6
95
N.A.
91.5
90.4
N.A.
72
66.5
78.6
76.1
N.A.
62.5
N.A.
65.1
N.A.
P-Site Identity:
100
93.3
86.6
60
N.A.
6.6
6.6
N.A.
6.6
20
40
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
6.6
20
N.A.
13.3
46.6
60
13.3
N.A.
6.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.9
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68
59.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
8
8
0
0
8
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
50
50
% D
% Glu:
8
0
0
8
15
0
15
8
0
0
15
0
15
0
15
% E
% Phe:
0
0
15
0
8
8
0
8
0
0
36
0
0
8
0
% F
% Gly:
15
29
8
15
15
0
8
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
22
8
0
0
8
0
% H
% Ile:
0
8
8
0
0
22
0
0
0
0
0
0
36
8
0
% I
% Lys:
8
22
15
15
0
8
15
15
15
8
0
0
15
0
8
% K
% Leu:
15
8
8
15
15
0
29
8
8
8
8
0
22
8
0
% L
% Met:
0
0
0
0
0
8
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
29
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
29
0
8
8
0
0
0
0
0
8
0
8
% P
% Gln:
0
8
0
0
0
15
0
15
15
15
15
8
8
8
8
% Q
% Arg:
8
0
0
0
0
8
0
8
43
8
8
15
0
0
0
% R
% Ser:
36
0
8
8
0
0
22
8
0
36
0
22
0
0
0
% S
% Thr:
8
0
29
0
8
8
0
15
0
0
0
36
0
0
8
% T
% Val:
8
8
8
0
0
15
0
0
0
0
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _